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spidmax="1026"/> </xml><![endif]--><!--[if gte mso 9]><xml> <o:shapelayout v:ext="edit"> <o:idmap v:ext="edit" data="1"/> </o:shapelayout></xml><![endif]--> </head> <style> body{ background:#e4e4e4; } </style> <body lang=EN-IN style='tab-interval:36.0pt'> <div class=WordSection1> <h3><span lang=EN-US style='mso-fareast-font-family:"Times New Roman"; mso-ansi-language:EN-US'>Abstract:<o:p></o:p></span></h3> <p class=MsoNormal style='text-align:justify'><span class=GramE><span lang=EN-US style='font-size:10.0pt;mso-ansi-language:EN-US'> </span><span lang=EN-US style='mso-ansi-language:EN-US'> </span><span lang=EN-US style='font-size:10.0pt;mso-ansi-language:EN-US'><span style='mso-spacerun:yes'> </span></span><span style='font-size:10.0pt'>Herein</span></span><span style='font-size:10.0pt'> we report an instant an d area that is sensitive and painful resonance (SPR) biosensor to detect progesterone (P4), a model <span class=SpellE>analyte</span> of little particles. A <span class=SpellE>terthiophene</span> s <span class=SpellE>caffold</span> with an <span class=SpellE>oligoethylene</span> glycol (OEG) linker is u <span class=SpellE>sed</span> as an anchor for the P4-ovalbumin <span class=GramE>( OVA</span>) immobilization on silver<span style='mso-spacerun:yes'>  </span>to<span style='mso-spacerun:yes'>  </span>form<span style='mso-spacerun:yes'>  </span>a<span style='mso-spacerun:yes'>  </span>stable,<span style='mso-spacerun:yes'>  </span><span class=SpellE>regenerable</span><span style='mso-spacerun:yes'>  </span>SPR<span style='mso-spacerun:yes'>  </span>area. Afterwards, inhibition SPR immunoassays b <span class=SpellE>ased</span> on this <span class=SpellE>terthiophene</span>/OVA-<span class=GramE>P4<span style='mso-spacerun:yes'>  </span>surface</span><span style='mso-spacerun:yes'>  </span>have actually<span style='mso-spacerun:yes'>  </span>demonstrated<span style='mso-spacerun:yes'>  </span>that<span style='mso-spacerun:yes'>  </span>P4restriction of detection (LOD) in buffer solution was 0.13 <span class=SpellE>ng</span> ml-1.As a result of the rapidity of every dimension (significantly less than 5 min per measurement), additionally the high sensitiveness of this assay, we think the sensing platform may hold p that is ideal for P4 detections.</span><span lang=EN-US style='font-size:10.0pt; mso-ansi-language:EN-US'><o:p></o:p></span></p> <p class=MsoNormal style='text-align:justify'><span lang=EN-US style='font-size:10.0pt;mso-ansi-language:EN-US'>. <o:p></o:p></span></p> <p class=MsoNormal><span lang=EN-US style='mso-fareast-font-family:"Times New Roman"; mso-ansi-language:EN-US'><br> <b>Keywords </b></span><span lang=EN-US style='font-size:10.0pt;mso-ansi-language: EN-US'>:</span><span lang=EN-US style='mso-fareast-font-family:"Times New Roman"; mso-ansi-language:EN-US'> </span><span class=SpellE><span style='font-size: 10.0pt'>terthiophene</span></span><span style='font-size:10.0pt'>, progesterone, area <span class=SpellE>plasmon</span> resonance, biosensor</span><span lang=EN-US style='mso-fareast-font-family:"Times New Roman";mso-ansi-language: EN-US'><o:p></o:p></span></p> </div> </body> </html>